Who’s starting, who’s hurt, and who’s on the move?
NFL news is nonstop, and we’re breaking it all down week by week this season.
Here’s the latest on what’s happening around the league entering Week 6:
Ceedee Lamb Misses Practice
Dallas Cowboys wide receiver Ceedee Lamb missed practice Wednesday as he continues to recover from an ankle injury he sustained in Week 3. While Lamb avoided being placed on injured reserve, he’s in real jeopardy of missing his third consecutive game. Dallas has gone 1-0-1 without Lamb and face the Carolina Panthers (2-3) on Sunday at 1 p.m. ET.
Alvin Kamara injures ankle at practice
New Orleans Saints running back Alvin Kamara reportedly sustained an ankle injury during practice on Wednesday. He was listed as a limited participant. The Saints will host the New England Patriots at 1 p.m. ET on Sunday. If Kamara were to miss the game, backup running back Kendre Miller would take the bulk of the carries.
49ers likely to be without top targets again
San Francisco 49ers head coach Kyle Shanahan expects his team to continue playing shorthanded when they face the Tampa Buccaneers on Sunday at 1:00 p.m. ET. On Wednesday, he said the 49ers are “not counting on” Ricky Pearsall returning in Week 6 and that tight end George Kittle is eyeing a Week 7 return.
Lamar Jackson Misses Practice
Baltimore Ravens quarterback Lamar Jackson missed practice on Wednesday as he continues to deal with the hamstring injury he sustained in Week 4. The Ravens have a bye week next week, so they may proceed with caution and hold Jackson out. The Ravens play the Los Angeles Rams on Sunday, and if Jackson is out again, Tyler Huntley will be the starting quarterback, rather than Cooper Rush, who started against the Houston Texans.
The Arizona Cardinals quarterback is dealing with a foot injury that kept him out of practice on Oct. 8, per NFL Media. Head coach Jonathan Gannon said the team is taking Murray’s situation “day by day.” The 2-3 Cardinals have a road matchup against the Indianapolis Colts in Week 6. Murray boasts an 88.6 passer rating, while completing 68.3% of his passes this season.
Colts add veteran linebacker
Indianapolis is signing linebacker Germaine Pratt, who was recently released by the Las Vegas Raiders, to a one-year deal, according to NFL Media. Through four games this season, Pratt has totaled 25 combined tackles and two passes defended and logged 110-plus combined tackles in both 2023 and 2024 with the Cincinnati Bengals. Pratt, who spent the first six seasons of his career with the Bengals (2019-24), reunites with Colts defensive coordinator Lou Anarumo, who was previously Cincinnati’s defensive coordinator from 2019-24.
Giants starting WR out
New York wide receiver Darius Slayton will likely miss the team’s Week 6 home matchup against the Philadelphia Eagles due to a hamstring injury, per ESPN. Slayton, who’s in the first season of a three-year, $36 million deal, has totaled 12 receptions for 166 yards this season.
Eagles’ OL Out With Ankle Injury
Eagles’ three-time Pro Bowler Landon Dickerson will reportedly be out the next 1-2 games with an ankle injury. Dickerson will miss the Eagles’ game against the New York Giants on Thursday Night Football.
Cardinals’ HC Jonathan Gannon receives fine
Cardinals head coach Jonathan Gannon reportedly received a team-induced fine of $100,000 for his sideline altercation with running back Emari Demercado. Gannon approached Demercado after the RB dropped the ball short of the end zone, yelling in his face and pushing him in his chest. The coach later apologized for his actions, but the team ultimately still issued a fine.
Jaguars TE Brenton Strange lands on IR
The Jacksonville Jaguars offense will be without a key piece for the foreseeable future after placing tight end Brenton Strange (hip) on injured reserve Tuesday. The hip injury will sideline Strange for, at least, the next four games.
In his five appearances this season, Strange has been a solid security blanket for Trevor Lawrence, ranking second on the team with 204 yards on 20 receptions.
Chargers make a move for Ravens edge Odafe Oweh
A pair of AFC teams made an intriguing trade Tuesday as the Los Angeles Chargers acquired Baltimore Ravens edge Odafe Oweh, per NFL Network. L.A. will receive Oweh and a future seventh-round pick while Baltimore will land safety Alohi Gilman and a 2026 fifth-round pick.
Oweh, the No. 31 overall pick in 2021, has recorded 10 tackles in five games played this season. His addition to a Chargers front seven currently without Khalil Mack (elbow) could prove beneficial going forward.
Meanwhile, Baltimore adds an experienced veteran to its struggling secondary in Gilman, a 2020 sixth-round pick. He has appeared in all five games in 2025, recording 22 tackles and three pass deflections.
Packers’ Watson returns to practice
Green Bay Packers wide receiver Christian Watson has returned to practice as he moves a step closer to playing again after tearing his anterior cruciate ligament nine months ago.
“I’ve got to knock a little bit of rust off, obviously,” Watson said after Monday’s practice. “Been a while since I was able to go out there and play football.”
Watson tore his right ACL on Jan. 5 during the Packers’ 24-22 loss to Chicago that closed their 2024 regular season. The Packers placed him on the physically unable to perform list before this season.
His return to practice starts a 21-day window before the Packers must activate him in order for him to play this year.
Watson, a 2022 second-round pick from North Dakota State, has 98 career catches for 1,653 yards and 14 touchdowns. He also has two career touchdown runs.
Patriots reportedly lose RB Gibson to ACL tear
The Patriots have lost kick returner and third-string running back Antonio Gibson to a torn ACL, per ESPN. He suffered the injury to his knee in Sunday’s win against the Bills, after taking additional snaps at running back. Gibson was filling in for starting running back Rhamondre Stevenson, who has fumbled the ball three times since Week 3, including against Buffalo – that leads the league.
The Associated Press contributed to this report.
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