With marijuana legalization expanding across regions, recent research reveals significant long-term mental health risks for adolescents who use cannabis.
Key Findings from Large-Scale Study
Researchers examined nearly 460,000 adolescents from Northern California’s Kaiser Permanente health system, following them until age 25. The study, led by Dr. Lynn Silver of the Public Health Institute, focused on otherwise healthy teens without prior mental illness signs. It specifically investigated whether cannabis use increases the likelihood of later psychiatric disorders.
The results show a clear connection: Teens reporting cannabis use in the past year face approximately double the risk of diagnosis with bipolar disorder or psychotic disorders, such as schizophrenia. These conditions rank among the most severe psychiatric illnesses, profoundly impacting daily life over decades.
Increased Risks by Disorder
Among the participants, around 4,000 teens developed bipolar disorder, and another 4,000 received psychotic disorder diagnoses. Cannabis-using teens also experienced a 33% higher rate of depression and a 25% increase in anxiety disorders. The association strengthens for younger adolescents, as their developing brains remain highly vulnerable.
Cannabis affects neural receptors critical to brain maturation, potentially altering developmental paths that manifest years later.
Broader Context and Implications
Mental health involves complex factors, including genetics, environment, and experiences. While cannabis alone does not cause these disorders, evidence suggests it can accelerate underlying vulnerabilities in some teens.
Schizophrenia, for instance, imposes substantial societal costs, estimated at $350 billion annually. As cannabis integrates more into daily life, ongoing scientific evaluation of its effects on young brains becomes essential to inform public health strategies.

